Evaluation of Acute and Chronic Toxicities of the Water Extract from Ziziphus attopensis Pierre

Table 2

Hematological values of male rats in chronic toxicity of ZA extract.

	Control	ZA extract
		1 g/kg	2 g/kg	4 g/kg	8 g/kg^a	8 g/kg^b
RBC (×10^6/μl)	8.15±0.09	8.13±0.17	7.86±0.25	7.81±0.10	7.44±0.37 *	7.86±0.09
HGB (g/dL)	15.64±0.14	15.38±0.29	14.99±0.44	15.11±0.12	15.22±0.03	15.37±0.13
HCT (%)	47.60±0.52	47.00±0.92	45.90±1.51	46.10±0.50	44.10±2.10 *	46.80±0.25
MCV (fl)	58.42±0.34	57.87±0.33	58.42±0.34	59.12±0.37	59.21±0.27	56.60±3.26
MCH (pg)	19.19±0.13	18.92±0.13	19.11±0.12	19.38±0.19	21.04±1.48 *	19.57±0.15
MCHC (g/dL)	32.84±0.08	32.68±0.14	32.70±0.18	32.75±0.28	35.52±2.46	32.52±0.33
Platelet (×10^5/μl)	6.48±0.72	7.54±0.55	6.99±0.84	8.31±0.36 *	7.24±0.48	7.86±0.30

Values are expressed as mean ± SEM, 𝑛=10.
*Significantly different from control, 𝑃<0.05.
^agroup was given ZA extract at 8 g/kg daily over 180 days.
^bA satellite group was given ZA extract at 8 g/kg daily over 180 days followed by no treatment for 28 days.