Table of Contents
ISRN Urology
Volume 2012, Article ID 789706, 4 pages
http://dx.doi.org/10.5402/2012/789706
Clinical Study

Decreased Vitamin B12 Levels in Children with Nocturnal Enuresis

1Department of Urology, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Yörükselim Mahallesi Hastane Caddesi 32, 46100 Kahramanmaras, Turkey
2Department of Pediatrics, Faculty of Medicine, Kahramanmaras Sutcu Imam University, 46100 Kahramanmaras, Turkey
3Department of Pediatric Surgery, Faculty of Medicine, Kahramanmaras Sutcu Imam University, 46100 Kahramanmaras, Turkey

Received 11 November 2011; Accepted 5 December 2011

Academic Editors: U. Barroso and H. Tezval

Copyright © 2012 Bülent Altunoluk et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objectives. Nocturnal enuresis is a common pediatric problem, the etiology of which is unclear. In the present study, vitamin B12 and folate levels were measured in children with nocturnal enuresis and compared with those in healthy control group children to investigate whether there was any relation with enuresis and neurogenic maturation as a first time in the literature. Methods. In this cross-sectional study, we included thirty children (16 girls, 14 boys) who had presented with primary nocturnal enuresis (PNE) complaints in the study group and 31 children (13 girls, 18 boys) in the control group. Body weight and height measurements were obtained and complete blood counts and vitamin B12 and folate levels were measured in all children. Results. No difference was found in age, height, and weight between study and control groups. Also the mean levels of the hemoglobin, hematocrit, and mean corpuscular volume (MCV) were not different between the two groups. Significantly lower mean vitamin B12 and folate levels were found in the enuresis group compared with the control group. Conclusions. Further studies are needed to clarify B12 and folate deficiency in larger series so that these tests can be included in routine investigations of enuretic children.