Research Article
Predictors of Conversion to Multiple Sclerosis in Patients with Clinical Isolated Syndrome Using the 2010 Revised McDonald Criteria
Table 2
Clinical and radiological predictors of CIS conversion to MS after 2 years.
| Demographic data | CIS cohort | MS cohort | P value | | |
| Sex | | | | Female | 21 (21.6%) | 34 (35.1%) | 0.4 | Male | 18 (18.6%) | 24 (24.7%) | 0.08 |
| Age (mean SD) | 30.21 6.70 | 24.64 6.77 | 0.01* |
| Age | | | | 30 years | 18 (18.6%) | 45 (46.4%) | 0.002* | 30 | 21 (21.6%) | 13 (13.4%) | 0.23 |
| Age at onset (mean SD) | 25.59 6.89 | 21.62 6.15 | 0.01* |
| Age at onset | | | | 30 years | 24 (24.7%) | 49 (50.5%) | 0.01* | 30 | 15 (15.5%) | 9 (9.3%) | 0.2 |
| Clinical presentation | | | | Optic nerve | 6 (6.2%) | 11 (11.3%) | 0.4 | Brainstem/cerebellum | 8 (8.2%) | 15 (15.5%) | 0.4 | Spinal cord | 11 (11.3%) | 19 (19.3%) | 0.5 | Supratentorial | 13 (13.4%) | 18 (18.6%) | 0.4 |
| Number of lesions in MRI | | | | No lesion | (2.1%) | 0 (0%) | | 1–3 lesions | 16 (16.5%) | 2 (3.4%) | 0.001* | 4–8 lesions | 16 (16.5%) | 21 (21.7%) | 0.2 | ≥9 lesions | 5 (5.2%) | 35 (36.1%) | 0.002* |
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*Statistically significant.
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