In Vitro-In Vivo Correlation Evaluation of Generic Alfuzosin Modified Release Tablets

Table 5

Descriptive pharmacokinetics properties of the test treatment under fasting conditions (𝑛=35).

Statistics	𝐾el	𝑇half	𝐶max	𝑇max	AUCT	AUCI	AUC_Exp
	(h^−1)	(h)	(ng/mL)	(h)	(ng/mL * h)	(ng/mL * h)
Mean	0.2779	7.89	11.4224	6.00	196.1723	211.4683	8.80
SD	0.10	0.87	2.23	0.49	12.0139	13.51	2.66
Min	0.1488	6.46	6.2445	4.33	119.1388	186.8190	4.92
Median	0.2191	7.16	9.3611	6.00	177.5498	179.5020	8.92
Max	0.4753	9.66	15.6322	8.00	250.6483	258.6327	15.53
CV%	37.13	30.13	26.89	50.55	36.22	37.04	30.26
Geometric mean	0.2524	7.75	11.9862	6.86	198.2896	213.2267	8.43
Harmonic mean	0.2397	7.59	11.6595	6.77	201.6518	216.2482	8.08