Application of Ion-Association Titration for the Assay of Cyproheptadine Hydrochloride in Pharmaceuticals

Table 1

Evaluation of intraday and interday precision and accuracy.

Method	CPH taken mg	Intraday (𝑛=7)			Interday (𝑛=5)
		CPH found^a	Precision^b	Accuracy^c	CPH found^a	Precision^b	Accuracy^c
Method A	6.0	6.04	1.08	0.65	6.08	1.68	0.87
	12.0	12.20	0.96	1.32	12.24	1.17	1.48
	18.0	18.12	1.18	1.24	18.15	1.33	1.36
Method B	4.0	4.06	1.29	1.08	4.09	1.36	1.45
	6.0	6.16	1.92	1.78	6.18	2.08	1.62
	8.0	8.14	1.75	1.44	8.16	1.92	1.75

^aMean value of n determinations.
^bRelative standard deviation (%).
^cBias (%): [(found − taken)/taken] ×100.