Application of Ion-Association Titration for the Assay of Cyproheptadine Hydrochloride in Pharmaceuticals

Table 3

Results of recovery study using the standard-addition method.

Formulation studied	Method A				Method B
	CPH in tablet, mg	Pure CPH added, mg	Total found, mg	Pure CPH recovered*, percent ± SD	CPH in tablet, mg	Pure CPH added, mg	Total found, mg	Pure CPH recovered*, percent ± SD
Practin	7.90	4.0	11.86	99.26±1.11	2.98	1.5	4.49	99.33±1.06
	7.90	8.0	16.15	103.22±1.82	2.98	3.0	6.10	102.3±1.97
	7.90	12.0	19.83	99.35±0.98	2.98	4.5	7.55	101.8±1.01
Ciplactin	5.92	3.0	8.96	101.72±1.45	2.96	1.5	4.40	99.25±1.26
	5.92	6.0	11.97	100.85±1.68	2.96	3.0	6.16	101.92±1.63
	5.92	9.0	15.22	103.07±2.07	2.96	4.5	7.72	102.04±1.12

*Mean value of three determinations.