Research Article

Conservation, Compensation, and Evolution of N-Linked Glycans in the HIV-1 Group M Subtypes and Circulating Recombinant Forms

Figure 2

Networks of positions with highly conserved glycosylation. Networks of highly conserved glycosylated pairs identified in each HIV-1 group M subtype/CRF. Pairs where greater than 90% of sequences exhibit glycosylation at both positions are joined by a line. In all cases, the networks are mutually dependent such that each position in the network is seen as highly dependent with every other position in the network. The number of sequence in each dataset is represented as while the percentage of sequences glycosylated at all of the positions in the network for the respective subtype/CRF is also shown. Positions that are predicted as N-linked glycosylated in less than 25% of sequences for a particular subtype/CRF are marked with a *.
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