Clinical Study

DNase1: No Association with Crohn's Disease in a New Zealand Population

Table 3

DNase1 activity by subphenotype.

Estimate (95% CI)P

Age at diagnosis<17−0.23 (−4.09–3.64)0.908
17 to 401.51 (−0.75–3.78)0.190
40<−2.37 (−6.39–1.65)0.247

CD behaviourinflammatory−0.16 (−2.66–2.35)0.903
stricturing1.96 (−1.01–4.93)0.195
penetrating0.88 (−3.32–5.07)0.681

CD locationIleal0.10 (−2.76–2.97)0.943
Colonic1.29 (−1.61–4.19)0.382
Ileocolonic0.38 (−2.69–3.44)0.809

Other IBD familyY0.50 (−4.56–5.57)0.846
Bowel resectionY1.38 (−1.47–4.23)0.340
EIMY−0.14 (−3.63–3.35)0.939
Perianal diseaseY−0.83 (−4.79–3.14)0.681
severityY1.05 (−2.48–4.59)0.559
SmokingY1.01 (−3.46–5.65)0.633