Dried Blood Spot Sampling with LC-MS Analysis for Routine Therapeutic Caffeine Monitoring in Neonates

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td align="left" rowspan="2"> </td><td align="center" colspan="3">Nominal conc. (ng/mL)</td></tr><tr class="thead"><td align="center">500</td><td align="center">8000</td><td align="center">25000</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td align="left">Recovery (%)</td><td align="center">47.0</td><td align="center">44.2</td><td align="center">44.9</td></tr><tr><td align="left">SD</td><td align="center">7.4</td><td align="center">2.3</td><td align="center">3.0</td></tr><tr><td align="left">Precision (CV%)</td><td align="center">15.6</td><td align="center">5.2</td><td align="center">6.6</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

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tab2

Table 2

Table 2: Dried Blood Spot Sampling with LC-MS Analysis for Routine Therapeutic Caffeine Monitoring in Neonates 