Collagen Extraction from Malaysian Cultured Catfish (Hybrid Clarias Sp.): Kinetics and Optimization of Extraction Conditions Using Response Surface Methodology

Table 2

Estimated coefficients of the fitted quadratic polynomial equation for different responses.

Parameter	Regression coefficient	Standard error	F value	P value	Indication
Linear
𝑋1	44.11	3.86	130.85	<0.0001	Significant
𝑋2	20.14	3.86	27.27	0.0004	Significant
𝑋3	21.60	3.86	31.38	0.0002	Significant
Quadratic
𝑋^21	−50.32	7.35	46.82	<0.0001	Significant
𝑋^22	−0.92	7.35	0.016	0.9034	Not significant
𝑋^23	−26.32	7.35	12.81	0.0050	Significant
Interaction
𝑋1𝑋2	6.61	4.31	2.35	0.1560	Not significant
𝑋1𝑋3	2.16	4.31	0.25	0.6266	Not significant
𝑋2𝑋3	−12.25	4.31	8.07	0.0175	Significant