Research Article

Desires, Need, Perceptions, and Knowledge of Assisted Reproductive Technologies of HIV-Positive Women of Reproductive Age in Ontario, Canada

Table 3

Univariate and multivariate logistic regression models of participant responses for need for ART.

CharacteristicsProblems becoming pregnantUnadjustedAdjusted
Yes ( 𝑛 = 7 2 )No ( 𝑛 = 3 5 3 )Odds ratio (95% CIs) 𝑃 valueOdds ratio (95% CIs) 𝑃 value

Age (years)38 (33, 43)38 (33, 44)
 18–252 (3%)18 (5%)11
 26–4044 (64%)181 (53%)2.19 (0.49, 9.78)0.311.60 (0.33, 7.69)0.56
 >4023 (33%)144 (42%)1.44 (0.31, 6.61)0.641.13 (0.23, 5.59)0.88
Ethnic background
 African25 (35%)168 (50%)1
 Caribbean7 (10%)33 (10%)1.43 (0.57, 3.57)0.45
 European-British10 (14%)33 (10%)2.04 (0.89, 4.64)0.09
 French-Canadian11 (15%)38 (11%)1.95 (0.88, 4.29)0.10
 Aboriginal8 (11%)30 (9%)1.79 (0.74, 4.35)0.20
 Other10 (14%)35 (10%)1.92 (0.85, 4.35)0.12
African ethnicity versus other0.55 (0.32, 0.93)0.03
Birth place
 Africa26 (37%)161 (47%)1
 Canada34 (48%)126 (37%)1.67 (0.95, 2.93)0.07
 Caribbean7 (10%)30 (9%)1.44 (0.58, 3.63)0.43
 Other4 (6%)25 (7%)0.99 (0.32, 3.08)0.99
Not born in Canada37 (51%)216 (61%)0.67 (0.40, 1.12)0.12
 Years in Canada (for those not  born in Canada)8 (3, 17)5 (2, 11)1.03 (0.99, 1.06)0.13
Toronto region33 (46%)181 (51%)0.80 (0.48, 1.34)0.40
Working27 (39%)129 (38%)1.04 (0.61, 1.77)0.88
On government assistance36 (51%)172 (50%)1.05 (0.63, 1.76)0.84
Marital status
 Married/common-law/living  with a partner34 (50%)152 (46%)1.08 (0.57, 2.05)0.82
 Divorced/widowed17 (25%)96 (29%)0.85 (0.41, 1.78)0.67
 Never married17 (25%)82 (25%)1
Education
 High school or higher43 (69%)204 (66%)1.14 (0.63, 2.06)0.66
 Less than high school19 (31%)103 (34%)1
Annual household income
 <20 K19 (30%)150 (51%)11
 20–40 K23 (37%)85 (29%)2.14 (1.10, 4.15)0.022.36 (1.16, 4.80)0.02
 >40 K21 (33%)60 (20%)2.76 (1.39, 5.50)<0.012.63 (1.25, 5.52)0.01
Years since diagnosis of HIV positive9 (4, 13)7 (4, 12)1.00 (0.99, 1.01)0.74
Hepatitis B co-infection3 (4%)9 (3%)1.60 (0.42, 6.08)0.49
Hepatitis C co-infection11 (15%)54 (16%)0.96 (0.47, 1.94)0.90
CD4 ≥ 200 cells/mm355 (92%)220 (90%)1.25 (0.46, 3.41)0.66
Recent VL (log10 copies/mL)4 (4, 5)4 (3, 4)1.90 (0.91, 3.97)0.09
Ever on HIV medication67 (93%)297 (85%)2.30 (0.88, 5.98)0.09
Currently on HIV treatment62 (86%)248 (72%)2.40 (1.18, 4.87)0.022.53 (1.12, 5.71)0.03  
Partner
 HIV negative27 (66%)105 (53%)1
 HIV positive14 (34%)92 (47%)0.59 (0.29, 1.20)0.14
In sexual relationship37 (52%)190 (54%)0.91 (0.55, 1.52)0.72
Monogamous relations35 (49%)181 (52%)0.91 (0.55, 1.52)0.73
Current contraceptive use30 (42%)115 (33%)1.43 (0.85, 2.41)0.17
Ever gave birth56 (79%)304 (87%)0.55 (0.29, 1.06)0.07
Lifetime pregnancies
 At least once23 (33%)61 (17%)11
 ≥247 (67%)288 (83%)0.43 (0.24, 0.77)<0.010.41 (0.21, 0.78)<0.01
Lifetime births
 At least once45 (63%)142 (41%)1
 ≥226 (37%)207 (59%)0.40 (0.23, 0.67)<0.001

VL: viral load.