Clinical Study

Clinical Significance of Preterm Singleton Pregnancies Complicated by Placental Abruption following Preterm Premature Rupture of Membranes Compared with Those without p-PROM

Table 1

Obstetric complications and perinatal outcomes of preterm singleton pregnancies complicated by placental abruption with and without preterm premature rupture of membranes (p-PROM).

p-PROM 𝑃 value*
(−)(+)

N6042
Maternal age (years) 3 1 . 9 ± 4 . 4 3 0 . 5 ± 4 . 6 0.16
Parity 0 . 8 ± 1 . 1 0 . 7 ± 0 . 7 0.59
Multiparous32 (50.0)18 (58.1)0.61
Gestational age at delivery
 Average (weeks) 3 3 . 3 ± 2 . 6 3 2 . 5 ± 3 . 5 0.26
 <32 weeks12 (18.8)10 (32.3)0.23
Hypertensive disorders6 (9.4)0 (0.0)0.19
Emergency Cesarean delivery52 (81.3)11 (35.5)<0.01
DIC12 (18.8)1 (3.2)0.08
Blood loss requiring transfusion13 (20.3)3 (9.7)0.34
Histological chorioamnionitis**
 Stage II14 (21.9)9 (29.0)0.61
 Stage III4 (6.3)8 (25.8)0.02
Neonatal birth weight
  Average (g)2, 0 0 6 ± 5 4 4 1, 8 9 1 ± 6 4 2 0.39
  Small for gestational age11 (17.2)6 (19.4)0.98
Fetal demise9 (14.1)1 (3.2)0.21
Surviving fetuses/neonates
𝑛 55 (85.9)30 (96.8)0.21
 NRFS41 (74.5)15 (50.0)0.04
 Apgar 1′ < 414 (25.5)2 (6.7)0.07
  Apgar 5′ < 44 (7.3)1 (3.3)0.77
  Umbilical artery pH < 79 (16.4)1 (3.3)0.14

Values are expressed as 𝑛 (%) or mean ± SD.
𝑃 values by Student’s 𝑡 -test or 𝜒 2 test.
**Microscopic histological analysis of the placenta.
p-PROM: preterm premature rupture of membranes.
DIC: disseminated intravascular coagulation.
NRFS: nonreassuring fetal status.