Figure 1: Summary of selected human GLUT4 promoter/CAT reporter constructs used to generate transgenic mice. The major regulatory domains (Domain 1, MEF2, and LXRE are shown. Expression of transgenic mRNA from white (W) and brown (B) adipose, skeletal muscle (S), heart (H), liver (L) and brain (Br). STZ indicates regulation under streptozotocin diabetes similar to endogenous. GLUT4.