Table of Contents
ISRN Materials Science
Volume 2012 (2012), Article ID 861643, 6 pages
Research Article

Characteristics of Molecularly Imprinted Polymer Thin Layer for Bisphenol A and Response of the MIP-Modified Sensor

1Department of Bioinformatics, Graduate School of Engineering, Soka University, 1-236 Tangi, Hachioji, Tokyo 192-8577, Japan
2Health Technology Research Center, National Institute of Advanced Industrial Science and Technology, 1-8-31 Midorigaoka, Ikeda, Osaka 563-8577, Japan
3RIKEN Quantitative Biology Center, 6-2-3 Furuedai, Suita, Osaka 565-0874, Japan

Received 1 September 2011; Accepted 12 October 2011

Academic Editor: J. Gruber

Copyright © 2012 Izumi Kubo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We examine the characteristics of molecularly imprinted polymer (MIP) layers for bisphenol A (BPA) to investigate the effect of their thickness on the performance of the BPA sensor. MIP thin layers for bisphenol A were polymerized on a sputtered gold electrode by UV light irradiation for 2 to 30 min. Their thickness, as determined by a QCM analyzer, was 3.6 ±  0.3 nm after 5 min of irradiation and increased as the irradiation time increased to 30 min. AFM images of the MIP-modified surface suggested that the gold electrode was covered with a smooth MIP layer. The anodic peaks of BPA and ascorbic acid caused by gold electrode and the MIP-modified electrode were compared, and the electrode with MIP polymerized for 5 min showed more selectivity to BPA than that polymerized for 2 min. The MIP thin layer thus has potential as a sensing element of a chemical sensor.