International Scholarly Research Notices / 2012 / Article / Tab 3 / Research Article
Strain Echocardiography in Early Detection of Doxorubicin-Induced Left Ventricular Dysfunction in Children with Acute Lymphoblastic Leukemia Table 3 Comparison between conventional echo, tissue Doppler parameters, and peak systolic strain in the main three longitudinal views of LV in controls and patients group before starting doxorubicin treatment.
Control (
𝑛
-30) Patient group (
𝑛
-25)
𝑡
-test
𝑃
valueFS %
3
5
.
7
8
±
5
.
1
6
4
0
±
4
.
8
7
2 0.05* E (m/sec)
0
.
8
7
±
0
.
1
1
0
.
7
7
±
0
.
2
4
2.1 0.04* A (m/sec)
0
.
5
2
±
0
.
1
3
0
.
7
3
±
0
.
1
3
3.3 0.005* E/A
1
.
5
1
±
0
.
4
1
.
6
0
±
0
.
4
2
1.1 0.09 s (m/sec)
0
.
0
7
±
0
.
0
2
0
.
0
6
±
0
.
0
1
4
0.9 0.15 IVCT (ms)
8
3
.
1
±
4
.
9
8
3
.
6
±
4
.
2
1.8 0.08
𝑒
′
(m/sec)
0
.
1
2
±
0
.
0
3
0
.
1
2
7
±
0
.
0
1
1
0.5 0.52
𝑎
′
(m/sec)
0
.
0
7
±
0
.
0
2
0
.
0
7
2
±
0
.
0
2
0
0.8 0.25
𝑒
′
/
𝑎
1
.
8
8
±
0
.
4
9
1
.
9
±
0
.
4
0.75 0.53 IVRT (ms)
6
6
.
2
±
3
.
6
6
7
.
1
±
3
.
3
1.99 0.057 ALX
−
2
2
.
2
±
5
.
8
%
−
2
1
.
1
±
5
.
3
%0.53 0.59 A4C −21±2.4%
−
1
8
.
9
±
4
.
5
%1.86 0.07 A2C −21±3.4%
−
1
6
.
9
±
7
.
3
%2.3 <0.03* G
−
2
1
.
5
±
2
.
2
%
−
1
8
.
7
±
4
.
5
%2.7 <0.01*
FS: fractional shortening,
𝐸
: peak early filling velocity,
𝐴
: Peak atrial phase filling velocity,
𝑠
′
: tissue Doppler peak mitral annulus systolic velocity,
𝑒
′
: tissue Doppler mitral flow early-phase filling velocity,
𝑎
′
: tissue Doppler peak atrial phase filling velocity, IVCT: isometric contraction time, IVRTL: Isometric relaxation time, ALX: apical long axis, A4C: apical 4-chamber, A2C: apical 2-chamber, views, and
𝐺
: global peak systolic strain.
