The Sweet Spot: Continued Search for the Glycemic Threshold for Macrovascular Disease—A Retrospective Single Center Experience

Table 2

Associations between glycemic classification and various demographic and clinical variables.

	Fasting blood glucose category
Characteristic	<90 mg/dL	90–99 mg/dL	100–125 mg/dL	126+ mg/dL	P value
	(𝑛=121)	(𝑛=142)	(𝑛=193)	(𝑛=100)
Age (mean ± s.d.)	49.8 ± 14.7^†	53.6 ± 13.9*	57.4 ± 11.4	58.1 ± 11.4	<0.0001
BMI	28.0 ± 5.1^§	28.8 ± 5.6	30.3 ± 5.3	33.5 ± 6.1^‡	<0.0001
% Male	47.9%	55.6%	55.4%	67.3%	0.04
Smoking
Never	70.0%	56.0%	41.9%	30.7%	<0.0001
Current	10.8%	26.2%	40.3%	44.6%
Past	19.2%	17.7%	17.8%	24.8%
Positive family history of CVD	48.8%	52.6%	24.1%	50.7%	<0.0001
Presence of HTN	38.3%	41.8%	65.6%	71.3%	<0.0001
ASCVD	13.2%	32.4%	48.7%	59.4%	<0.0001^ℓ

^†On multiple pairwise comparisons (Bonferroni correction of P value) the mean age for the patients with fasting blood glucose <90 was significantly different from the 100–125 and 126+ groups, respectively (𝑃<0.0001).
*On multiple pairwise comparisons (Bonferroni correction of P value) the mean age for the patients with fasting blood glucose 90–99 was significantly different from the 100–125 and 126+ groups, respectively (𝑃=0.045).
^§On multiple pairwise comparisons (Bonferroni correction of P value) the mean BMI for the patients with fasting blood glucose <90 was significantly different than the 100–125 group (𝑃=0.003).
^‡On multiple pairwise comparisons (Bonferroni correction of P value) the mean BMI for the patients with fasting blood glucose 126+ was significantly different from all of the other groups (𝑃<0.0001).
^ℓBoth the Pearson chi-square and the chi-square test for trend were statistically significant (𝑃<0.0001).