Table of Contents
ISRN Obstetrics and Gynecology
Volume 2012, Article ID 916914, 6 pages
Review Article

Genesis of Preeclampsia: An Epidemiological Approach

1Scientific Research Institute, Universidad Juárez del Estado de Durango, Avenida Universidad y Volantín no Number, 34000 Durango, DGO, Mexico
2Department of Family Medicine, University Hospital Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, 64460 Monterrey, NL, Mexico

Received 8 October 2011; Accepted 13 November 2011

Academic Editor: A. Canellada

Copyright © 2012 Jaime Salvador-Moysén et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


There are analyzed some of the main aspects related to the causality of preeclampsia, privileging two types of models: the clinic model and the epidemiologic model, first one represented by the hypothesis of the reduced placental perfusion and the second one considering the epidemiologic findings related to the high levels of psychosocial stress and its association with preeclampsia. It is reasoned out the relevance of raising the causality of the disease from an interdisciplinary perspective, integrating the valuable information generated from both types, clinical and epidemiologic, and finally a tentative explanatory model of preeclampsia is proposed, the subclinical and sociocultural aspects that predispose and trigger the disease are emphasized making aspects to stand out: the importance of reduced placental perfusion as an indicator of individual risk, and the high levels of physiological stress, as a result of the unfavorable conditions of the psychosocial surroundings (indicator of population risk) of the pregnant women.