Review Article

Blood Loss and Massive Transfusion in Patients Undergoing Major Oncological Surgery: What Do We Know?

Table 2

Perioperative interventions targeted to reduce blood loss during major oncological surgery.

Type of surgeryAnesthetic interventionsSurgical interventions

Spine tumorsAntifibrinolyticsSurgical hemostasis
Controlled hypotension*Preoperative tumor embolization

Sacral tumorsAntifibrinolyticsSurgical hemostasis
Preoperative tumor embolization
Aortic balloon occlusion-Iliac artery ligation

HemipelvectomyAntifibrinolyticsSurgical hemostasis
Vascular control

Nephrectomy with IVC embolectomyAntifibrinolyticsSurgical hemostasis
Correction of hypothermia after CPB

Liver and multivisceral resectionCVP < 5 cm H2O**Surgical hemostasis
AntifibrinolyticsPreoperative tumor embolization
Vascular control

Extrapleural pneumonectomiesAntifibrinolyticsSurgical hemostasis

*Controlled hypotension has fallen in disfavor of many anesthesiologists due to its possible association with postoperative visual loss. **This practice has also been questioned due to the poor correlation between central venous pressure and central volume status.