Method Development and Validation for the Simultaneous Determination of Fexofenadine Hydrochloride and Montelukast Sodium in Drug Formulation Using Normal Phase High-Performance Thin-Layer Chromatography
Table 1
Linear regression data for calibration curves ().
Parameters
FEX
MTKT
Linearity range
2400–10800 ng spot−1
200–900 ng spot−1
Slope ± Standard error
Intercept ± Standard error
−
Confidence limit of slopea
1.620 to 1.682
6.796 to 7.003
Confidence limit of intercepta
798.1 to 1240
−77.73 to 45.49
0.9996
0.9998
Sy.xb
98.19
27.38
P valuec
<0.0001
<0.0001
a95% confidence intervals.
bStandard deviation of residuals from line.
cP value is < 0.0001, considered extremely significant.