Mild External Compression of the Leg Increases Skin and Muscle Microvascular Blood Flow and Muscle Oxygenation during Simulated Venous Hypertension
Anterior tibial skin (a) and muscle (b) microvascular blood flows measured by photoplethysmography (PPG) during 3 experimental conditions. Mild external leg compression of 40 mmHg alone does not affect skin and muscle perfusion in a supine healthy subject. Simulated venous hypertension using a 65 mmHg thigh tourniquet decreases skin microvascular blood flow by 62% and muscle microvascular blood flow by 68%. Mild external leg compression of 40 mmHg during venous hypertension doubles skin microvascular blood flow compared to the simulated venous hypertension alone. * repeated measures ANOVA.