Eradication Treatment of Helicobacter pylori Infection: Its Importance and Possible Relationship in Preventing the Development of Gastric Cancer

Table 1

Recommended regimens for the treatment of H. pylori infection in adults.

Treatment duration (days)	Recommended regimens (all drugs administered orally)
7–10	Clarithromycin (500 mg, b.i.d.) + amoxicillin (1 g, b.i.d.) + ranitidine bismuth citrate (400 mg, b.i.d.)
7–10	Clarithromycin (500 mg, b.i.d.) + amoxicillin (1 g, b.i.d.) + ranitidine bismuth citrate (400 mg, b.i.d.) + omeprazole (20 mg, b.i.d.) [or lanzoprazole (30 mg, b.i.d.) or pantoprazole (40 mg, b.i.d.)]
14	Metronidazole (400 to 500 mg, t.i.d. or q.i.d.) + colloidal bismuth subcitrate (120 mg, q.i.d.) + tetracycline (basic phosphate or oxytetracycline) (500 mg, q.i.d.)
7–10	Metronidazole (400 to 500 mg, b.i.d. or t.i.d.) + amoxicillin (500 mg, b.i.d. or t.i.d.) + omeprazole (20 mg, b.i.d.) [or lanzoprazole (30 mg, b.i.d.) or pantoprazole (40 mg, b.i.d.)]
4–7	Metronidazole (400 to 500 mg, t.i.d. or q.i.d.) + colloidal bismuth subcitrate (120 mg, q.i.d.) + tetracycline (basic phosphate or oxytetracycline) (500 mg, q.i.d.) + omeprazole (20 mg, b.i.d.) [or lanzoprazole (30 mg, b.i.d.) or pantoprazole (40 mg, b.i.d.)]
7	Clarithromycin (500 mg, b.i.d.) + metronidazole (400 to 500 mg, b.i.d.) + ranitidine bismuth citrate (400 mg, b.i.d.)
7	Clarithromycin (500 mg, b.i.d.) + metronidazole (400 to 500 mg, b.i.d.) + omeprazole (20 mg, b.i.d.) [or lanzoprazole (30 mg, b.i.d.) or pantoprazole (40 mg, b.i.d.)]
7	PPI (standard dose, q.d.) + clarithromycin (500 mg, b.i.d.) + furazolidone (200 mg, b.i.d.)^*
7	PPI (standard dose, q.d.) + furazolidone (200 mg, t.i.d.) + tetracycline (500 mg, q.i.d.)^*
7	Bismuth (standard dose, b.i.d.) + tetracycline (500 mg, b.i.d.) + furazolidone (200 mg, b.i.d.) + PPI (standard dose, b.i.d.) or ranitidine (standard dose, b.i.d.)^*
10	Levofloxacin (500 mg, q.d.) + amoxicillin (1 g, b.i.d.) + PPI (standard dose, b.i.d.)
10	Levofloxacin (500 mg, q.d.) + amoxicillin (500 mg, q.i.d.) + PPI (standard dose, b.i.d.) + bismuth (standard dose, q.i.d.)
14	Rifabutin (150 mg, b.i.d.) + amoxicillin (500 mg, b.i.d.) + PPI (standard dose, b.i.d.)

^*Treatments used in Brazilian patients.