Amelioration of Obesity, Glucose Intolerance, and Oxidative Stress in High-Fat Diet and Low-Dose Streptozotocin-Induced Diabetic Rats by Combination Consisting of “Curcumin with Piperine and Quercetin”

Table 1

Effect of CPQ extract on oxidative stress parameters in high-fat diet and low-dose streptozotocin-induced diabetic rats.

Groups	SOD (U/mL)	CAT (U/mL)	GSH-Px ( μmole/gHb)
Normal control	8.39±0.02 **	3.54±0.03 **	0.00059±0.001 **
Normal STZ control	4.51±0.03	1.32±0.13	0.0038±0.001
HFD control	6.62±0.12 **	2.10±0.01 **	0.0042±0.002 **
HFD + STZ control	4.38±0.13	1.08±0.02 **	0.00283±0.0017
CPQ (50 mg/kg/day)	7.91±0.03 **	2.80±0.16 **	0.0048±0.003 **
CPQ (100 mg/kg/day)	9.05±0.03 **	3.31±0.01 **	0.005±0.003 **
Curcumin (100 mg/kg/day)	6.82±0.027 **	2.57±0.02 **	0.0049±0.001 **

Values are mean ± SEM; 𝑁=6; **𝑃<0.01 as compared to HFD + STZ control.