Research Article

Liquid Chromatographic Method for the Quantification of Antipsychotic Agent Iloperidone in Pharmaceutical Formulation

Table 1

Regression analysis of the calibration curve and summary of validation parameters.

ParametersILO

Linearity range (μg/mL)0.1–20
Slope60966
Standard deviation of slope (SD)320.69
Intercept2697.64
Standard deviation of intercept (SD)405.28
Correlation coefficient0.9996
Detection limit (μg/mL)0.022
Quantitation limit (μg/mL)0.067
Accuracy (%)99.26–100.33
Precision (RSDa, %)
Intraday precision ( 𝑛 = 3 )0.33–1.06
Interday precision ( 𝑛 = 3 )0.41–1.14
Repeatability study (RSDa, %)0.49

a RSD is relative standard deviation and, “n” is the number of determinations.