Table of Contents
ISRN Otolaryngology
Volume 2012, Article ID 965204, 6 pages
Review Article

Particle Beam Therapy for Cancer of the Skull Base, Nasal Cavity, and Paranasal Sinus

Department of Radiation Oncology, Ibaraki Prefectural Central Hospital, 6528, Koibuchi, Kasama 309-1793, Japan

Received 25 February 2012; Accepted 9 April 2012

Academic Editors: C. Y. Chien, S. Kanzaki, M. Tahara, and D. Thurnher

Copyright © 2012 Nobuyoshi Fukumitsu. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Particle beam therapy has been rapidly developed in these several decades. Proton and carbon ion beams are most frequently used in particle beam therapy. Proton and carbon ion beam radiotherapy have physical and biological advantage to the conventional photon radiotherapy. Cancers of the skull base, nasal cavity, and paranasal sinus are rare; however these diseases can receive the benefits of particle beam radiotherapy. This paper describes the clinical review of the cancer of the skull base, nasal cavity, and paranasal sinus treated with proton and carbon ion beams, adding some information of feature and future direction of proton and carbon ion beam radiotherapy.