International Scholarly Research Notices / 2012 / Article / Tab 5

Research Article

Effect of Chemical Enhancers in Transdermal Permeation of Alfuzosin Hydrochloride

Table 5

Skin irritation effect of different chemical enhancers.

Chemical enhancer with concentrationSkin irritation

Citric acid (2.5%) 0
Oleic acid (5%) 0
Isopropyl myristate (10%) 0
N-lauroyl sarcosine (2%) 2
Tween-20 (2%) 1
Transcutol (20%) 1
Dimethyl sulfoxide (10%) 2
N-methyl pyrrolidone (10%)3

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