Research Article

Inhibitory Effects of Trehalose on Malignant Melanoma Cell Growth: Implications for a Novel Topical Anticancer Agent on the Ocular Surface

Table 2

Summary of flow cytometric results for ratios of ATM, P53, Chk2, or p-cdc25 positive cells in various concentrations of trehalose in culture media in Figure 8.

怀ATM+P53+Chk2+p-cdc25+

Control0.0%1.7%0.2%0.4%
5% trehalose0.9%4.8%1.9%1.9%
7.5% trehalose6.2%7.5%4.9%4.9%

Abbreviations: ATM: ataxia telangiectasia mutated; Chk: check kinase; p-cdc: phosphorylated cell division cycle.