Table of Contents
ISRN Endocrinology
Volume 2012 (2012), Article ID 970629, 8 pages
http://dx.doi.org/10.5402/2012/970629
Research Article

Effects of a Physical Activity Program on Markers of Endothelial Dysfunction, Oxidative Stress, and Metabolic Status in Adolescents with Metabolic Syndrome

1Centro de Investigación en Ciencias Médicas, Universidad Autónoma del Estado de México, 50130 Toluca Estado de México, Mexico
2Facultad de Química, Universidad Autónoma del Estado de México, 50120 Toluca Estado de México, Mexico
3Centro de Adiestramiento en Investigación Clínica, Coordinación de Investigación en Salud, Instituto Mexicano del Seguro Social, México, DF, Mexico
4Unidad de Investigación Médica en Trombosis, Hemostasia y Aterogénesis, Instituto Mexicano del Seguro Social, Apartado Postal 12-1100, México, DF, Mexico

Received 11 April 2012; Accepted 15 May 2012

Academic Editors: P. Balagopal and C.-F. Kwok

Copyright © 2012 Eneida Camarillo-Romero et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The metabolic syndrome (MetS) is a precursor of diabetes. Physical activity (PA) improves endothelial dysfunction and may benefit patients with MetS. Aims. To evaluate the effect of a physical activity (PA) program on markers of endothelial dysfunction and oxidative stress in adolescents with (MetS). Methods. We carried out a cohort study of 38 adolescents with and without MetS (18 females and 20 males). All participants completed a 3-month PA program. All variables of the MetS as well as markers of endothelial dysfunction and oxidative stress tests were evaluated. Results. Females with and without MetS showed significant differences for almost all components of the MetS, whereas males were significantly different in half of the components. After the PA program, components of the MetS were not different from baseline values except for HDL-C levels. Some baseline endothelial dysfunction markers were significantly different among adolescents with and without MetS; however, after the PA program, most of these markers significantly improved in subjects with and without MetS. Conclusion. PA improves the markers of endothelial dysfunction in adolescents with MetS although other changes in the components of the MetS were not observed. Perhaps the benefits of PA on all components of MetS would appear after a PA program with a longer duration.