Implication of DNA Methylation Profiling in Oral Epithelium for Lung Cancer Screening

Table 3

Methylation frequencies of GDNF, RARB, and HS3ST2 according to subgroup analysis.

	GDNF	𝑃	RARB	𝑃	HS3ST2	𝑃
Current and former smokers
Patients (𝑛=11)	4	0.0072	3	0.1142	3	0.1142
Controls (𝑛=17)	0		1		1
Never smokers
Patients (𝑛=5)	3	0.0369	3	0.0098	1	0.0756
Controls (𝑛=15)	2		1		0
Age > 50 years
Patients (𝑛=16)	7	0.0143	6	0.1025	4	0.1441
Controls (𝑛=16)	1		2		1