Clinical Study

Implication of DNA Methylation Profiling in Oral Epithelium for Lung Cancer Screening

Table 5

Diagnostic value of the combined analysis.

ā€‰SensitivitySpecificityPPVNPV

Total participants37.5%96.8%85.7%75.6%
Current and former smokers27.3%94.1%75.0%66.7%
Never smokers60.0%100%100%88.2%
Age > 50 years43.7%93.8%88.2%62.5%

PPV: positive predictive value; NPV: negative predictive value.