Research Article

Glycosaminoglycans Modify Elastase Action In Vitro and Enhance Elastase-Induced Cell Death in Cultured Fibroblasts

Table 2

Effect of GAGs on secondary structure of elastase.

Sample 𝛼 helix (%)Antiparallel 𝛽 sheet (%)Parallel 𝛽 sheet (%) 𝛽 turn (%)Randon (%)Total (%)

HNE4.5040.05.3020.235.0105
HNE + HS11.329.25.5020.035.5101
HNE + C6S86.50.2002.902.92.3094.7

HS: heparan sulfate; C6S: chondroitin 6-sulfate.