Table of Contents
ISRN Transplantation
Volume 2013, Article ID 102590, 7 pages
http://dx.doi.org/10.5402/2013/102590
Clinical Study

Sicker Patients for Liver Transplantation: Meld, Meld Sodium, and Integrated Meld’s Prognostic Accuracy in the Assessment of Posttransplantation Events at a Single Center from Argentina

1Hepatology Unit, Hospital Italiano de Buenos Aires, Avenida Presidente Perón 1500, Derqui, B1629HJ Buenos Aires, Argentina
2Liver Transplant Unit, Hospital Italiano de Buenos Aires, Avenida Presidente Perón 1500, Derqui, B1629HJ Buenos Aires, Argentina
3Adult Intensive Care Unit, Hospital Italiano de Buenos Aires, Avenida Presidente Perón 1500, Derqui, B1629HJ Buenos Aires, Argentina

Received 23 May 2013; Accepted 21 August 2013

Academic Editors: A. D. Hess and A. Jaramillo

Copyright © 2013 Federico Piñero et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. P. S. Kamath, R. H. Wiesner, M. Malinchoc et al., “A model to predict survival in patients with end-stage liver disease,” Hepatology, vol. 33, no. 2, pp. 464–470, 2001. View at Publisher · View at Google Scholar · View at Scopus
  2. E. Cholongitas, L. Marelli, V. Shusang et al., “A systematic review of the performance of the Model for End-Stage Liver Disease (MELD) in the setting of liver transplantation,” Liver Transplantation, vol. 12, no. 7, pp. 1049–1061, 2006. View at Publisher · View at Google Scholar · View at Scopus
  3. D. M. Heuman, S. G. Abou-Assi, A. Habib et al., “Persistent ascites and low serum sodium identify patients with cirrhosis and low MELD scores who are at high risk for early death,” Hepatology, vol. 40, no. 4, pp. 802–810, 2004. View at Publisher · View at Google Scholar · View at Scopus
  4. S. W. Biggins, W. R. Kim, N. A. Terrault et al., “Evidence-based incorporation of serum sodium concentration into MELD,” Gastroenterology, vol. 130, no. 6, pp. 1652–1660, 2006. View at Publisher · View at Google Scholar · View at Scopus
  5. A. Luca, B. Angermayr, G. Bertolini et al., “An integrated MELD model including serum sodium and age improves the prediction of early mortality in patients with cirrhosis,” Liver Transplantation, vol. 13, no. 8, pp. 1174–1180, 2007. View at Publisher · View at Google Scholar · View at Scopus
  6. M. R. Foxton, M. A. B. Al-Freah, A. J. Portal et al., “Increased model for end-stage liver disease score at the time of liver transplant results in prolonged hospitalization and overall intensive care unit costs,” Liver Transplantation, vol. 16, no. 5, pp. 668–677, 2010. View at Publisher · View at Google Scholar · View at Scopus
  7. W. R. Kim, R. H. Wiesner, P. S. Kamath et al., “Prediction of liver transplant outcome using the MELD scale,” Transplantation, vol. 71, supplement 1, p. 284, 2001. View at Google Scholar
  8. H. Y. Yoo and P. J. Thuluvath, “Short-term postliver transplant survival after the introduction of MELD scores for organ allocation in the United States,” Liver International, vol. 25, no. 3, pp. 536–541, 2005. View at Publisher · View at Google Scholar · View at Scopus
  9. A. Lally, A. Nixon, D. Lewis et al., “MELD, CTP and region 1 CMSS equally predict post liver transplant patient survival,” Hepatology, vol. 34, article 290, 2001. View at Google Scholar
  10. S. Saab, V. Wang, A. B. Ibrahim et al., “MELD score predicts 1-year patient survival post-orthotopic liver transplantation,” Liver Transplantation, vol. 9, no. 5, pp. 473–476, 2003. View at Publisher · View at Google Scholar · View at Scopus
  11. H. Y. Yoo and P. J. Thuluvath, “Short-term postliver transplant survival after the introduction of MELD scores for organ allocation in the United States,” Liver International, vol. 25, no. 3, pp. 536–541, 2005. View at Publisher · View at Google Scholar · View at Scopus
  12. K. V. N. Menon, S. L. Nyberg, W. S. Harmsen et al., “MELD and other factors associated with survival after liver transplantation,” American Journal of Transplantation, vol. 4, no. 5, pp. 819–825, 2004. View at Publisher · View at Google Scholar · View at Scopus
  13. N. M. Desai, K. C. Mange, M. D. Crawford et al., “Predicting outcome after liver transplantation: utility of the model for end-stage liver disease and a newly derived discrimination function,” Transplantation, vol. 77, no. 1, pp. 99–106, 2004. View at Publisher · View at Google Scholar · View at Scopus
  14. A. Habib, I. Duorchik, J. Ahmad et al., “MELD as predictor of post-transplantation,” Hepatology, vol. 40, article 261, 2004. View at Google Scholar
  15. W. R. Kim, S. W. Biggins, W. K. Kremers et al., “Hyponatremia and mortality among patients on the liver-transplant waiting list,” The New England Journal of Medicine, vol. 359, no. 10, pp. 1018–1026, 2008. View at Publisher · View at Google Scholar · View at Scopus
  16. E. Rodrigo, G. Fernández-Fresnedo, J. C. Ruiz et al., “Assessment of glomerular filtration rate in transplant recipients with severe renal insufficiency by nankivell, Modification of Diet in Renal Disease (MDRD), and Cockroft-Gault equations,” Transplantation Proceedings, vol. 35, no. 5, pp. 1671–1672, 2003. View at Publisher · View at Google Scholar · View at Scopus
  17. P. S. Kamath and W. R. Kim, “The model for end-stage liver disease (MELD),” Hepatology, vol. 45, no. 3, pp. 797–805, 2007. View at Publisher · View at Google Scholar · View at Scopus
  18. R. S. Brown Jr., K. S. Kumar, M. W. Russo et al., “Model for end-stage liver disease and child-turcotte-pugh score as predictors of pretransplantation disease severity, posttransplantation outcome, and resource utilization in united network for organ sharing status 2A patients,” Liver Transplantation, vol. 8, no. 3, pp. 278–284, 2002. View at Publisher · View at Google Scholar · View at Scopus
  19. N. M. Desai, K. C. Mange, M. D. Crawford et al., “Predicting outcome after liver transplantation: utility of the model for end-stage liver disease and a newly derived discrimination function,” Transplantation, vol. 77, no. 1, pp. 99–106, 2004. View at Publisher · View at Google Scholar · View at Scopus
  20. M. Jacob, L. P. Copley, J. D. Lewsey et al., “Pretransplant MELD score and post liver transplantation survival in the UK and Ireland,” Liver Transplantation, vol. 10, no. 7, pp. 903–907, 2004. View at Publisher · View at Google Scholar · View at Scopus
  21. M. F. Dawwas, J. D. Lewsey, J. M. Neuberger, and A. E. Gimson, “The impact of serum sodium concentration on mortality after liver transplantation: a cohort multicenter study,” Liver Transplantation, vol. 13, no. 8, pp. 1115–1124, 2007. View at Publisher · View at Google Scholar · View at Scopus
  22. B. C. Yun, W. R. Kim, J. T. Benson et al., “Impact of pretransplant hyponatremia on outcome following liver transplantation,” Hepatology, vol. 49, no. 5, pp. 1610–1615, 2009. View at Publisher · View at Google Scholar · View at Scopus
  23. L. Massicotte, D. Beaulieu, J.-D. Roy et al., “MELD score and blood product requirements during liver transplantation: no link,” Transplantation, vol. 87, no. 11, pp. 1689–1694, 2009. View at Publisher · View at Google Scholar · View at Scopus