Sicker Patients for Liver Transplantation: Meld, Meld Sodium, and Integrated Meld’s Prognostic Accuracy in the Assessment of Posttransplantation Events at a Single Center from Argentina

Table 1

Characteristics of cirrhotic patients who underwent liver transplantation (𝑁=152).

Parameter	𝑁=152
Age (yr)	52.5±11
Male gender (%)	59.3
Hepatitis C (%)	23.6
DM* (%)	14.4
Child pugh	10.5±4
MELD	23±9
MELD Na1	28±13
MELD Na2	26±9
iMELD	47±16
Total bilirubin (mg/dL)*	10±7
INR*	2.17±1.8
Creatinine (mg/dL)*	1.2±0.49
GFR-MDRD mL/min*	72±23
Hyponatremia <130 mEq/L* (%)	17.7
Hyponatremia <126 mEq/L* (%)	5.9
Hypernatremia >145 mEq/L* (%)	1.9
Ascites* (%)	76.9
Hepatic encephalopathy*(%)	58.5
Donor age	40±26
Donor BMI	26±4
Donor natremia (mEq/L)	151±11
Donor macrosteatosis >30% (%)	25.8
CIT (minutes)	467±67
Surgery time (minutes)	318±38
WIT (minutes)	52±4
RRT after LT (%)	3.9
Total blood products (units)	45±38
Monoclonal antibodies induction (%)	25
HAT (%)	3.9
PVT (%)	0.65
Biliary complications (%)	9.8

Note. Normal values: creatinine 0.6–1.1 mg/dL, serum sodium 135–145 mEq/L. ∗Pre-LT variables.
BMI: body mass index; CIT: cold ischemic time; DM: diabetes mellitus before LT; GFR-MDRD: glomerular filtration rate calculated by Modification of Diet in Renal Disease equation; HAT: hepatic artery thrombosis after liver transplantation; MELD: Model for End-Stage Liver Disease: 9.6 × logn (Creat mg/dL) + 3.8 × logn (tot bil mg/dL) + 11.2 × logn (RIN) + 6.4; MELD Na1: MELD sodium 1: MELD + 1.59 × (135-patient's serum sodium mEq/L); MELD Na2: MELD sodium 2: MELD-Na − [0.025 × MELD × (140 − Na)] + 140; iMELD: integrated MELD: MELD + (age × 0.3) − (0.7 × Na p) + 100; INR: international normalized ratio; WIT: warm ischemic time; RRT: renal replacement therapy; total blood products: total blood products consumption during the first 48 hrs after Liver Transplantation; monoclonal antibodies induction: use of Basiliximab (20 mg day 0 and 20 mg day 4); PVT: portal vein thrombosis after LT.