Research Article
Stochastic Model for In-Host HIV Dynamics with Therapeutic Intervention
Table 1
(a) Variables for the stochastic model. (b) Parameters for the stochastic model.
(a) |
| Variable | Description | Initial condition |
| | The concentration of uninfected CD4 cells at time | 100 | | The concentration of infected CD4 cells at time | 0.02 | | The concentration of virus particles at time | 0.001 |
|
|
(b) |
| Parameter symbol | Parameter description | Estimate |
| | The reverse transcriptase inhibitor drug effect | 0.5 | | The protease inhibitor drug effect | 0.5 | | The total rate of production of healthy CD4 cells | 10 | | The per capita death rate of healthy CD4 cells | 0.02 | | The transmission coefficient between uninfected CD4 cells and infective virus particles | 0.000024 | | Per capita death rate of infected CD4 cells | 0.5 | | The virus production rate due to risk behaviors | 0.001 | | The per capita death rate of infective virus particles | 3 | | The death rate of infected but not yet virus producing cell | 0.5 | | Time lag during infection | 0.5 | | The average number of infective virus particles produced by an infected CD4 cell in the absence of treatment during its entire infectious lifetime | 1000 |
|
|