Serum NGAL in Critically Ill Children in ICU from a Single Center in Egypt

Table 1

Laboratory investigations of study groups regarding liver and kidney functions.

Parameter	Control 𝑁=15	Patients 𝑁=60	Test of significance	𝑃
Total bilirubin (mg/dL)
Median	0.4	0.5	1.25^b	0.210
Range	(0.3–0.8)	(0.3–23.4)
Direct bilirubin (mg/dL)
Median	0.1	0.5	0.99^b	0.321
Range	(0.1–0.2)	(0.1–12.9)
ALT (U/L)
Median	31	45.5	1.11^b	0.26
Range	(12–42)	(9–133)
AST (U/L)
Median	38	55.6	3.007^b	0.003*
Range	(5–55)	(18–1207)
Albumin (g/dL)
X′ ± SD	(3.907 ± 0.371)	(3.36 ± 0.618)	3.245^a	0.002*
TP (g/dL)
X′ ± SD	(6.8 ± 0.442)	(5.7 ± 0.868)	4.47^a	0.001*
Urea (mg/dL)
Median	25.8	35.5	3.42^b	0.001*
Range	(15–37)	(15–116)
Creatinine (mg/dL)
X′ ± SD	0.65 ± 0.22	0.68 ± 0.22	0.38^a	0.69
WBCs (×103/cmm)	12.1 (6.1–14.1)	13.1 (2.1–56.2)	0.64^b	0.51
Hb (g/dL )	12.5 (9.5–15.5)	10.5 (6.6–18)	6.26^b	0.001*
Platelet (×109/cmm)	250 (180–340)	222 (35–1008)	0.49^b	0.62
NGAL-0 (ng/mL)	54 (44–141)	88.5 (34–210)	2.47^b	0.01*

Test of significance: ^at-test; ^bMann-Whiney test; *significant.