Table of Contents
ISRN Hypertension
Volume 2013, Article ID 165937, 10 pages
http://dx.doi.org/10.5402/2013/165937
Review Article

Hypertension: The Neglected Complication of Transplantation

Hypertension Section, Internal Medicine Department, Hospital Italiano de Buenos Aires, Juan D. Perón 4190, C1181ACH Buenos Aires, Argentina

Received 10 March 2013; Accepted 11 April 2013

Academic Editors: A. A. Noorbala, R. S. Padwal, and D. G. Romero

Copyright © 2013 Lucas S. Aparicio et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Arterial hypertension and transplantation are closely linked, and its association may promote impaired graft and overall survival. Since the introduction of calcineurin inhibitors, it is observed in 50–80% of transplanted patients. However, many pathophysiological mechanisms are involved in its genesis. In this review, we intend to provide an updated overview of these mechanisms, dealing with the causes common to all kinds of transplantation and emphasizing special cases with distinct features, and to give a perspective on the pharmacological approach, in order to help clinicians in the management of this frequent complication.