Research Article

Role of Calcium Channels in Heavy Metal Toxicity

Figure 4

Effect of dihydropyridines on Cd cytotoxicity in VDCC-expressing CHOCα cells. Cells were treated for 30 min in (a) control medium containing 30 mM KCl, (b) , (c) nimodipine, (d) . Note the partial recovery in shape of the cells treated in the presence of nimodipine and definitive lost of adhesion when the treatment was performed in the presence of BayK. . The graph (e) represents counts of viable adherent cells in the same experiment (average in 3 samples) in control (basal), following for a 30 min treatment with 100  Cd (Cd), (K), and 1 μM nimodipine (N), and and 1 μM BayK (B). * indicates significantly different from control with , and ** with .
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