Research Article

Role of Calcium Channels in Heavy Metal Toxicity

Figure 5

Evidence of Cd-induced apoptosis: change in cell capacitance. Cells were incubated with 100  Cd for 60 minutes, and electrical measurements were performed 24 h after wash. Membrane capacitance was estimated from transient compensation (see Section 2.4). Bars represent mean . Treatment with Cd caused shrinkage of all cell, as revealed by reduction of the cell capacitance in both wild-type ( in control and with Cd treatment) and CHOC cells ( in control and with Cd treatment). Nimodipine protected CHOC cells from Cd-induced shrinkage ( ). * indicates significantly different from control with , and ** with .
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