The Role of Interleukin-1 Genotype in the Association between Coronary Heart Disease and Periodontitis in a Syrian Population

Table 4

Genotype frequency of polymorphisms in the IL-1 gene cluster by the varying degrees of ABL.

	Alveolar bone loss
Genotype frequency	Mild		Moderate		Severe		P value
	𝑛	%	𝑛	%	𝑛	%
IL-1α +4845
1.1	19	95%	49	51%	33	39%	<0.001
Combination 1.2 + 2.2	1	5%	47	49%	51	61%
IL-1β +3954
1.1	14	70%	57	59%	36	43%	0.025
Combination 1.2 + 2.2	6	30%	39	41%	48	57%
IL-1β  −511
1.1	9	45%	25	26%	49	58%	<0.001
Combination 1.2 + 2.2	11	55%	71	74%	35	42%
IL-1 RA VNTR
1.1	9	45%	44	46%	50	60%	0.154
Combination 1.2 + 2.2	11	55%	52	54%	34	40%