Clinical Study
The Role of Interleukin-1 Genotype in the Association between Coronary Heart Disease and Periodontitis in a Syrian Population
Table 4
Genotype frequency of polymorphisms in the IL-1 gene cluster by the varying degrees of ABL.
| | Alveolar bone loss | | Genotype frequency | Mild | Moderate | Severe | P value | | | % | | % | | % | |
| IL-1α +4845 | | | | | | | | 1.1 | 19 | 95% | 49 | 51% | 33 | 39% | <0.001 | Combination 1.2 + 2.2 | 1 | 5% | 47 | 49% | 51 | 61% | IL-1β +3954 | | | | | | | | 1.1 | 14 | 70% | 57 | 59% | 36 | 43% | 0.025 | Combination 1.2 + 2.2 | 6 | 30% | 39 | 41% | 48 | 57% | IL-1β −511 | | | | | | | | 1.1 | 9 | 45% | 25 | 26% | 49 | 58% | <0.001 | Combination 1.2 + 2.2 | 11 | 55% | 71 | 74% | 35 | 42% | IL-1 RA VNTR | | | | | | | | 1.1 | 9 | 45% | 44 | 46% | 50 | 60% | 0.154 | Combination 1.2 + 2.2 | 11 | 55% | 52 | 54% | 34 | 40% |
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