Table of Contents
ISRN Dermatology
Volume 2013 (2013), Article ID 203941, 4 pages
http://dx.doi.org/10.1155/2013/203941
Research Article

The Role of 39 Psoriasis Risk Variants on Age of Psoriasis Onset

1Department of Dermatology, University of California San Francisco, 2340 Sutter Street, P.O. Box 0808, San Francisco, CA 94143-0808, USA
2Department of Gastroenterology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Digestive Diseases, Shanghai 200001, China
3University of California Irvine School of Medicine, Irvine, CA 92697, USA
4University of Utah School of Medicine, Salt Lake City, UT 84132, USA
5Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA
6Chicago College of Osteopathic Medicine, Downers Grove, IL 60515, USA

Received 16 July 2013; Accepted 29 August 2013

Academic Editors: B. Amichai, G. Chodorowska, C. Ferrándiz, and A. Tosca

Copyright © 2013 Yingchang Lu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. T. Henseler and E. Christophers, “Psoriasis of early and late onset: characterization of two types of psoriasis vulgaris,” Journal of the American Academy of Dermatology, vol. 13, no. 3, pp. 450–456, 1985. View at Google Scholar · View at Scopus
  2. C. Ferrándiz, R. M. Pujol, V. García-Patos, X. Bordas, and J. A. Smandía, “Psoriasis of early and late onset: a clinical and epidemiologic study from Spain,” Journal of the American Academy of Dermatology, vol. 46, no. 6, pp. 867–873, 2002. View at Google Scholar
  3. M. H. Allen, H. Ameen, C. Veal et al., “The major psoriasis susceptibility locus PSORS1 is not a risk factor for late-onset psoriasis,” Journal of Investigative Dermatology, vol. 124, no. 1, pp. 103–106, 2005. View at Publisher · View at Google Scholar · View at Scopus
  4. J. E. Guojónsson, A. Kárason, A. A. Antonsdóttir et al., “HLA-Cw6-positive and HLA-Cw6-negative patients with psoriasis vulgaris have distinct clinical features,” Journal of Investigative Dermatology, vol. 118, no. 2, pp. 362–365, 2002. View at Publisher · View at Google Scholar · View at Scopus
  5. F. Capon, M.-J. Bijlmakers, N. Wolf et al., “Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene,” Human Molecular Genetics, vol. 17, no. 13, pp. 1938–1945, 2008. View at Publisher · View at Google Scholar · View at Scopus
  6. Y. Liu, C. Helms, W. Liao et al., “A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci,” PLoS Genetics, vol. 4, no. 3, Article ID e1000041, 2008. View at Publisher · View at Google Scholar · View at Scopus
  7. R. P. Nair, K. C. Duffin, C. Helms et al., “Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways,” Nature Genetics, vol. 41, no. 2, pp. 199–204, 2009. View at Google Scholar
  8. P. E. Stuart, R. P. Nair, E. Ellinghaus et al., “Genome-wide association analysis identifies three psoriasis susceptibility loci,” Nature Genetics, vol. 42, no. 11, pp. 1000–1004, 2010. View at Google Scholar
  9. E. ELinghaus, D. ELinghaus, P. E. Stuart et al., “Genome-wide asociation study identifies a psoriasis susceptibility locus at TRAF3IP2,” Nature Genetics, vol. 42, no. 11, pp. 991–995, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. U. Hüffmeier, S. Uebe, A. B. Ekici et al., “Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis,” Nature Genetics, vol. 42, no. 11, pp. 996–999, 2010. View at Google Scholar
  11. A. Strange, F. Capon, C. C. Spencer et al., “A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1,” Nature Genetics, vol. 42, no. 11, pp. 985–990, 2010. View at Google Scholar
  12. R. de Cid, E. Riveira-Munoz, P. L. J. M. Zeeuwen et al., “Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis,” Nature Genetics, vol. 41, no. 2, pp. 211–215, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. L. C. Tsoi, S. L. Spain, J. Knight et al., “Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity,” Nature Genetics, vol. 44, no. 12, pp. 1341–1348, 2012. View at Google Scholar
  14. J. T. Elder, A. T. Bruce, J. E. Gudjonsson et al., “Molecular dissection of psoriasis: integrating genetics and biology,” Journal of Investigative Dermatology, vol. 130, no. 5, pp. 1213–1226, 2010. View at Google Scholar
  15. B. N. Howie, P. Donnelly, and J. Marchini, “A flexible and accurate genotype imputation method for the next generation of genome-wide association studies,” PLoS Genetics, vol. 5, no. 6, Article ID e1000529, 2009. View at Publisher · View at Google Scholar · View at Scopus
  16. P. I. de Bakker, M. A. R. Ferreira, X. Jia, B. M. Neale, S. Raychaudhuri, and B. F. Voight, “Practical aspects of imputation-driven meta-analysis of genome-wide association studies,” Human Molecular Genetics, vol. 17, no. R2, pp. R122–R128, 2008. View at Publisher · View at Google Scholar · View at Scopus
  17. H. Chen, G. Hayashi, O. Y. Lai et al., “Psoriasis patients are enriched for genetic variants that protect against HIV-1 disease,” PLoS Genetics, vol. 8, no. 2, Article ID e1002514, 2012. View at Google Scholar
  18. J. G. Bergboer, A. M. Oostveen, M. E. de Jager et al., “Paediatric-onset psoriasis is associated with ERAP1 and IL23R loci, LCE3C_LCE3B deletion and HLA-C*06,” British Journal of Dermatology, vol. 167, no. 4, pp. 922–925, 2012. View at Google Scholar
  19. H. Chen, A. Poon, C. Yeung et al., “A genetic risk score combining ten psoriasis risk loci improves disease prediction,” PLoS ONE, vol. 6, no. 4, Article ID e19454, 2011. View at Publisher · View at Google Scholar · View at Scopus