Analysis of CYP2D6 Allele Frequencies and Identification of Novel SNPs and Sequence Variations in Sardinians

Table 1

Class list of major CYP2D6 isoenzyme substrates [3, 4].

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CYP2D6 isoenzyme major substrates

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Tricyclic antidepressants

Tetracyclic antidepressants

Selective serotonin reuptake inhibitors

Serotonin-norepinephrine reuptake inhibitors

Opioids

Antipsychotics

Selective estrogen receptor modulator

𝛽-blockers

Antihypertensives

Antiarrhythmics

Antitussives

Antiemetics

Antidiabetics

Histamine antagonists

Dopamine antagonists

Antimitotics

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