Table of Contents
ISRN Organic Chemistry
Volume 2013, Article ID 217675, 5 pages
http://dx.doi.org/10.1155/2013/217675
Research Article

New L-Serine Derivative Ligands as Cocatalysts for Diels-Alder Reaction

1REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências da Universidade do Porto, Rua do Campo Alegre s/n, 4169-007 Porto, Portugal
2Centro de Investigação em Química, Departamento de Química e Bioquímica, Faculdade de Ciências da Universidade do Porto, Rua do Campo Alegre s/n, 4169-007 Porto, Portugal

Received 1 October 2013; Accepted 21 October 2013

Academic Editors: P. S. Andrada, M. W. Paixao, and N. Zanatta

Copyright © 2013 Carlos A. D. Sousa et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

New L-serine derivative ligands were prepared and tested as cocatalyst in the Diels-Alder reactions between cyclopentadiene (CPD) and methyl acrylate, in the presence of several Lewis acids. The catalytic potential of the in situ formed complexes was evaluated based on the reaction yield. Bidentate serine ligands showed good ability to coordinate medium strength Lewis acids, thus boosting their catalytic activity. The synthesis of the L-serine ligands proved to be highly efficient and straightforward.