Effects of Propofol, a Sedative-Hypnotic Drug, on the Lipid Profile, Antioxidant Indices, and Cardiovascular Marker Enzymes in Wistar Rats

Table 1

Effects of propofol on serum biochemical indices in the rats.

Grouping	Protein	ALT	AST	UREA	CREAT	TOTAL BIL
	(mg/mL)	(IU/L)	(IU/L)	(𝜇mol/L)	(𝜇mol/L)	(𝜇mol/L)
Control	0.10±0.03	337.9±16.7	565.9±23.4	34.3±5.80	7.57±0.81	56.9±4.80
Propofol (2 mg/kg)	0.11±0.02	346.9±18.4	515.3±33.9	37.6±7.05	7.72±0.66	86.7±6.62^∗
Propofol (4 mg/kg)	0.12±0.02	359.6±21.3	527.4±44.3	32.8±6.10	7.87±0.64	87.0±8.92 *

Values are means ± SD of 7 animals per group.
∗Significantly different from control (𝑃<0.05).
ALT: alanine aminotransferase, AST: aspartate aminotransferase, CREAT: creatinine, and TOTAL BIL: total bilirubin.