Effects of Propofol, a Sedative-Hypnotic Drug, on the Lipid Profile, Antioxidant Indices, and Cardiovascular Marker Enzymes in Wistar Rats

Table 2

Effects of propofol on serum lipid profile of the rats.

Grouping	Serum
	TC	TG	HDL-C	LDL-C
	(mmol/L)	(mmol/L)	(mmol/L)	(mmol/L)
Control	97.5±3.68	122.1±13.89	28.2±3.55	69.8±5.32
Propofol (2 mg/kg)	169.7±8.42^∗	240.7±22.36	16.6±2.98^∗	101.4±5.37^∗
Propofol (4 mg/kg)	151.3±5.54^∗	262.0±16.05	12.9±2.68^∗	124.1±8.03^∗

Values are means ± SD of 7 animals per group.
*Significantly different from control (𝑃<0.05).
TC: total cholesterol, TG: triglycerides, HDL-C: high-density lipoprotein-cholesterol, and LDL-C: low-density lipoprotein-cholesterol.