Effects of Propofol, a Sedative-Hypnotic Drug, on the Lipid Profile, Antioxidant Indices, and Cardiovascular Marker Enzymes in Wistar Rats

Table 3

Effects of propofol on nonenzymatic antioxidant parameters in the rats.

Grouping	LPO (nmol MDA/mg protein)			GSH (𝜇g/g tissue)
	Serum	Kidney	Liver	Kidney	Liver
Control	22.0±3.45	18.5±1.62	18.9±3.55	5.87±1.31	10.1±3.12
Propofol (2 mg/kg)	24.1±4.03	16.2±2.36	19.3±4.16	4.65±0.72	14.3±2.40^∗
Propofol (4 mg/kg)	21.8±3.01	18.7±1.87	21.0±3.10	5.01±0.63	13.7±2.30^∗

Values are means ± SD of 7 animals per group.
*Significantly different from control (𝑃<0.05).
LPO: lipid peroxidation, GSH: reduced glutathione.