Table of Contents
ISRN Spectroscopy
Volume 2013, Article ID 230858, 12 pages
Review Article

A Recent Review on Chemiluminescence Reaction, Principle and Application on Pharmaceutical Analysis

1Department of Pharmacy, College of Medicine and Health Sciences, Ambo University, Ambo 19, Ethiopia
2Department of Pharmaceutical Chemistry and Pharmacognosy, Addis Ababa University, Addis Ababa 117, Ethiopia

Received 16 July 2013; Accepted 15 September 2013

Academic Editors: V. M. Bermudez, H. J. Byrne, and Z. Wang

Copyright © 2013 Tadesse Haile Fereja et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


This paper provides a general review on principle of chemiluminescent reactions and their recent applications in drug analysis. The structural requirements for chemiluminescent reactions and the different factors that affect the efficiency of analysis are included in the review. Chemiluminescence application in immunoassay is the new version for this review. Practical considerations are not included in the review since the main interest is to state, through the aforementioned applications, that chemiluminescence has been, is, and will be a versatile tool for pharmaceutical analysis in future years.