Addition of Multimodal Therapy to Standard Management of Steady State Sickle Cell Disease
Table 2
Steady state plasma levels of unconjugated bilirubin in HbSS individuals before and 12 months after addition of omega-3 fatty acids and potassium thiocyanate to standard management with folic acid and paludrine.
Study identity number
Plasma unconjugated bilirubin level (umol/L)
Pretreatment
Posttreatment
1
4.3
4.1
2
7
4.4
3
25.6
11
4
4.2
4.5
7
4
7.7
8
23
9.8
9
4
16.5
10
3
22
11
10
27
12
14
20
13
1
19.3
14
14
21
Median ()
5.65
13.75
value (2-tailed, Mann-Whitney test pre- versus posttreatment data)
