Characterization of the Mechanical Strength, Resorption Properties, and Histologic Characteristics of a Fully Absorbable Material (Poly-4-hydroxybutyrate—PHASIX Mesh) in a Porcine Model of Hernia Repair

Table 1

Description of composition, degradation mechanism, and expected human resorption time of absorbable mesh materials.

Mesh type		Composition	Degradation mechanism	Resorption time
DEXON	Covidien; (Mansfield, MA)	Polyglycolic acid (PGA)	Hydrolysis	2-3 months
VICRYL	Ethicon, Inc.; (Somerville, NJ)	Copolymer of glycolide; and lactide	Hydrolysis	2-3 months
GORE BIO-A	W.L. Gore & Assoc., Inc. (Flagstaff, AZ)	Copolymer of poly(glycolide: trimethylene carbonate)	Hydrolysis and enzymatic mechanisms	6 months
TIGR Matrix	Novus Scientific; (Uppsala, Sweden)	Comprised of 2 fibers with differing composition and resorption time
Fiber no. 1		Copolymer of polyglycolide, polylactide, and polytrimethylene carbonate	Hydrolysis	4 months
Fiber no. 2		Copolymer of polylactide and polytrimethylene carbonate	Hydrolysis	36 months
PHASIX	C. R. Bard, Inc./Davol Inc.; (Warwick, RI)	Poly-4-hydroxybutyrate (P4HB)	Hydrolysis and enzymatic mechanisms	12–18 months