Xanthine Oxidase Does Not Contribute to Apoptosis after Brain Hypoxia-Ischemia in Immature Rabbits

Table 1

Physiologic parameters during cerebral hypoxia-ischemia and reperfusion (mean ± SD).

	Baseline	Hypoxia	Ischemia	Reperfusion	Reperfusion	Reperfusion
		7 minutes	7 minutes	30 minutes	60 minutes	240 minutes
Mean arterial pressure (mmHg)
Control	91±9	106±20	88±15	87±4	85±5	77±33
Xanthine	95±5	102±11	94±10	95±6	90±3	97±12
Allopurinol	100±7	94±17	96±4	95±19	86±9	85±4
Intracranial pressure (mmHg)
Control	5±3	13±8	100±17	5±4	6±5	1±2
Xanthine	1±1	10±6	109±8	3±2	5±3	2±3
Allopurinol	2±2	9±2	107±4	3±2	4±4	2±2
Cerebral perfusion pressure (mmHg)
Control	87±7	93±14	0±0	82±7	79±6	76±32
Xanthine	94±5	92±10	0±0	93±4	86±2	95±10
Allopurinol	98±8	84±16	0±0	93±18	82±9	83±3
Esophageal temperature (°C)
Control	39.8±0.7	39.7±0.2	40.0±0.2	39.8±0.7	39.9±0.4	39.5±0.2
Xanthine	39.9±0.1	39.4±0.2	39.8±0.1	39.7±0.3	39.9±0.4	39.3±0.1
Allopurinol	39.8±0.6	39.4±0.1	39.9±0.3	39.5±0.5	39.9±0.7	39.5±0.2
Brain temperature (°C)
Control	39.3±0.3	39.3±0.2	39.0±0.2	38.9±0.5	39.2±0.3	38.4±0.6
Xanthine	39.1±0.3	38.9±0.1	38.9±0.3	38.8±0.4	39.3±0.4	38.6±0.1
Allopurinol	39.1±0.3	38.9±0.1	39.1±0.3	38.6±0.4	39.3±0.5	38.7±0.0