The Role of Neurotransmitters in Protection against Amyloid-β Toxicity by KiSS-1 Overexpression in SH-SY5Y Neurons
Figure 10
Effect of GABA receptor antagonism on KiSS-1 gene overexpression neuroprotection against amyloid-β toxicity. PKiSS cells were pretreated with the GABA-A antagonist 1(S),9(R)-(−)-bicuculline methiodide (BIC: 50 μM) for 2 h prior to exposure to Aβ 1–40 (10 μM) and determination of viability by MTT reduction. Results are mean ± s.e.m. * versus control (media alone); one-way ANOVA.
